CTDSPL protein (His tag) (80R-2152)
Purified recombinant Human CTDSPL protein (His tag)
|Synonyms||RBSP3 protein, PSR1 protein, HYA22 protein, CTD small phosphatase like protein, CTD small phosphatase-like protein, SCP3 protein|
Coomassie Blue stained SDS-PAGE of CTDSPL protein (His tag) (80R-2152)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MGSHMKYLLP EVTVLDYGKK CVVIDLDETL VHSSFKPISN ADFIVPVEID GTIHQVYVLK RPHVDEFLQR MGQLFECVLF TASLAKYADP VADLLDRWGV FRARLFRESC VFHRGNYVKD LSRLGRELSK VIIVDNSPAS YIFHPENAVP VQSWFDDMTD TELLDLIPFF EGLSREDDVY SMLHRLCNR|
|Purity||> 90% pure|
|Molecular Weight||23.9 kDa|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CTDSPL preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Recombinant human CTDSPL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
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