CTSD protein (30R-3257)

Purified recombinant CTSD protein

Synonyms Cathepsin D protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Images

SDS-PAGE analysis of CTSD protein (30R-3257)

Specifications

Expression System E.coli
Purity > 90% pure
Molecular Weight 64 kDa
Form & Buffer Supplied in liquid form in PBS buffer with 20 mM GSH

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance Cathepsin-D is an aspartic protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes where it degrades insulin. Along with Asp-protonation, lower pH also leads to conformational switch in cathepsin-D : the N terminal segment of the protease moves out of the active site as pH drops.

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Images

  • SDS-PAGE analysis of CTSD protein (30R-3257)

Availability: In stock

Price: $210.00
Size: 50 ug
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