CTSS protein (His tag) (80R-2655)
Purified recombinant Human CTSS protein (His tag)
|Synonyms||Cathepsin S protein, MGC3886 protein|
SDS-PAGE analysis of CTSS protein (His tag) (80R-2655)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||17-331 aa: MGSSHHHHHH SSGLVPRGSH MQLHKDPTLD HHWHLWKKTY GKQYKEKNEE AVRRLIWEKN LKFVMLHNLE HSMGMHSYDL GMNHLGDMTS EEVMSLMSSL RVPSQWQRNI TYKSNPNWIL PDSVDWREKG CVTEVKYQGS CGACWAFSAV GALEAQLKLK TGKLVSLSAQ NLVDCSTEKY GNKGCNGGFM TTAFQYIIDN KGIDSDASYP YKAMDQKCQY DSKYRAATCS KYTELPYGRE DVLKEAVANK GPVSVGVDAR HPSFFLYRSG VYYEPSCTQN VNHGVLVVGY GDLNGKEYWL VKNSWGHNFG EEGYIRMARN KGNHCGIASF PSYPEI|
|Method of Purification||CTSS protein was purified using Protein G affinity chromatography|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Cathepsin S, also known as CTSS, is a member of the peptidase C1 family. This protein is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. CTSS can function as an elastase over a broad pH range in alveolar macrophages. Recombinant human CTSS protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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