CTSZ protein (His tag) (80R-3034)
Purified recombinant CTSZ protein (His tag)
|Synonyms||Cathepsin Z preproprotein protein, Cathepsin Z protein, CTSX protein|
SDS-PAGE analysis of CTSZ protein (His tag) (80R-3034)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||62-303 aa: MGSSHHHHHH SSGLVPRGSH MGSLPKSWDW RNVDGVNYAS ITRNQHIPQY CGSCWAHAST SAMADRINIK RKGAWPSTLL SVQNVIDCGN AGSCEGGNDL SVWDYAHQHG IPDETCNNYQ AKDQECDKFN QCGTCNEFKE CHAIRNYTLW RVGDYGSLSG REKMMAEIYA NGPISCGIMA TERLANYTGG IYAEYQDTTY INHVVSVAGW GISDGTEYWI VRNSWGEPWG ERGWLRIVTS TYKDGKGARY NLAIEEHCTF GDPIV|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea|
Storage & Safety
|Storage||Store at 4 deg C for short term storage, for long term storage aliquot and store at -20 deg C or -70 deg C, avoid repeated freeze thaw cycles.|
|Biological Significance||In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.|
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