CXCL13 protein (His tag) (80R-3570)
Purified recombinant CXCL13 protein (His tag)
|Synonyms||Chemokine (C-X-C motif) ligand 13 protein, ANGIE protein, ANGIE2 protein, BCA-1 protein, BCA1 protein, BLC protein, BLR1L protein, SCYB13 protein, CXCL 13 protein, CXCL-13 protein|
Coomassie blue stained SDS-PAGE of CXCL13 protein (His tag) (80R-3570)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||23-109 aa: MGSSHHHHHH SSGLVPRGSH MGSVLEVYYT SLRCRCVQES SVFIPRRFID RIQILPRGNG CPRKEIIVWK KNKSIVCVDP QAEWIQRMME VLRKRSSSTL PVPVFKRKIP|
|Purity||> 85% pure|
|Method of Purification||CXCL13 protein was purified by using conventional chromatography techniques|
|Molecular Weight||12.7 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.|
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