CXCR6 antibody (70R-10500)
Affinity purified rabbit polyclonal CXCR6 antibody
|Synonyms||Polyclonal CXCR6 antibody, Anti-CXCR6 antibody, TYMSTR antibody, CXCR 6 antibody, CXCR-6 antibody, CXCR-6, chemokine, BONZO antibody, CD186 antibody, C-X-C motif receptor 6 antibody, CXCR 6, STRL33 antibody, CXCR6|
|Immunogen||CXCR6 antibody was raised in rabbit using the N terminal of CXCR6 as the immunogen|
|Assay Information||CXCR6 Blocking Peptide, catalog no. 33R-1131, is also available for use as a blocking control in assays to test for specificity of this CXCR6 antibody|
Western Blot analysis using CXCR6 antibody (70R-10500)
CXCR6 antibody (70R-10500) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.|
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