Cyclin E1 antibody (20R-2953)

Rabbit polyclonal Cyclin E1 antibody

Synonyms Polyclonal Cyclin E1 antibody, Anti-Cyclin E1 antibody, CCNE1 antibody, cyclin E1 antibody, BOS_17331 antibody, CCNE antibody, cyce antibody, CycE1 antibody, cycE3 antibody, CYCLE antibody, cyclinE antibody, cyclin E antibody, cyclin E3 antibody, cyclin Es antibody, cyclin Et antibody, fa18e07 antibody, G1/S-specific cyclin-E1 antibody, G1/S-specific cyclin-E3 antibody
Cross Reactivity Human, Mouse, Rat
Applications IHC-P, WB
Immunogen Cyclin E1 antibody was raised in Rabbit using a recombinant human protein purified from E.coli (His-Cyclin E1) as the immunogen

Images

Western Blot analysis using Cyclin E1 antibody (20R-2953)

Specifications

Host Rabbit
Isotype IgG
Method of Purification Cyclin E1 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1: 2000, IHC-P

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Cyclins play a key role in the orderly progression of the cell division cycle through their timed expression and their ability to bind, activate and enhance substrate affinity of their associated cyclin-dependent protein kinases (CDKs). E-type cyclins (cyclin E1 and cyclin E2) are expressed during the late G1 phase of the cell cycle until the end of the S-phase. Cyclin E binds and activates the kinase Cdk2 and by phosphorylating its substrates, the cyclic/Cdk2 complexes initiate a cascade of events that leads to the expression of S-phase specific genes. Besides this specific function as a regulator of S-phase-entry, cyclin E plays a direct role in the initiation of DNA replication, the control of genomic stability, and the centrosome cycle.

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Images

  • Western Blot analysis using Cyclin E1 antibody (20R-2953) |

Availability: In stock

Price: $295.00
Size: 100 ul
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