Cytokeratin 7 antibody (10R-7962)

Mouse monoclonal Cytokeratin 7 antibody

Synonyms Monoclonal Cytokeratin 7 antibody, Anti-Cytokeratin 7 antibody, Keratin K7 antibody, Cytokeratin 7
Cross Reactivity Canine, Feline, Goat, Hamster, Human, Mouse, Rat, Zebrafish
Applications FC, IHC, IHC-F, WB
Immunogen Cytokeratin 7 antibody was raised in Mouse using cytokeratins from the human bladder carcinoma cell line T24 as the immunogen.

Specifications

Host Mouse
Clone RCK105
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations FC: 1:100-1:200, IHC: 1:100-1:200, WB: 1:100-1:1000

General Information

Biological Significance Keratin K7 is found to occur in the columnar and glandular epithelium of the lung, cervix, breast, bile ducts, larger collecting ducts of the kidney and in mesothelium, but is absent from gastrointestinal epithelium, hepatocytes and myoepithelium. Several types of adenocarcinomas of the urinary tract are negative, while adenocarcinomas of the mammary gland, ovary and lung are positive. In colorectal carcinoma early stages are reported to be negative but advanced stages of tumor development are positive for keratin K7 expression. In immunoblotting the antibody is reactive with the 54 kDa keratin K7 protein (formerly also designated cytokeratin 7).

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Availability: In stock

Price: $315.00
Size: 100 ug
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