Cytokeratin 8 antibody (10R-C177ax)

Mouse monoclonal Cytokeratin 8 antibody

Synonyms Monoclonal Cytokeratin 8 antibody, Anti-Cytokeratin 8 antibody, Cytokeratin 8, Cytokeratin 8 antibody, Cytokeratin 8, Cytokeratin -8, Keratin K8 antibody, Cytokeratin -8 antibody
Specificity Human cytokeratin 8
Cross Reactivity Hamster, human, mouse, opossum, rat, treeshrew
Applications IHC-F, IHC-P, WB
Immunogen Cytokeratin 8 antibody was raised in mouse using cytoskeletal proteins from cultured Hela cells as the immunogen.

Specifications

Host Mouse
Clone Ks8.7
Isotype IgG1
Method of Purification Protein A affinity chromatography
Form & Buffer Supplied as a lyophilized powder. Reconstitute in 1 ml dist. water (final solution contains 0.09 % NaN3, 0.5% BSA in PBS buffer, pH 7.4)

Usage & Assay Information

Usage Recommendations IHC-F: 1:10, IHC-P: 1:10

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin, type I cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. It is often paired with keratin 18.

References
Add a Paper

Rodrigo Fernandez-Valdiviaa, Atish Mukherjeea, Yan Yinga, Jie Lia, Marilene Paquetb, Francesco J. DeMayoa, John P. Lydon

The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse

Developmental Biology

Volume: 328 Issue: 1 Page: 127-139 DOI: 10.1016/j.ydbio.2009.01.019

Fawzia Bardag-Gorce, Joan Oliva, Jun Li, Barbara A. French, Samuel W. French

SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model

Experimental and Molecular Pathology

Volume: 88 Issue: 3 Page: 353-362 DOI: 10.1016/j.yexmp.2010.03.001

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: $295.00
Size: 50 ug
OR
Shipping
View Our Distributors