DCK antibody (10R-1380)

Mouse monoclonal DCK antibody

Synonyms Monoclonal DCK antibody, Anti-DCK antibody, Deoxycytidine kinase antibody, MGC138632 antibody, MGC117410 antibody
Specificity Human DCK
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen DCK antibody was raised in mouse using recombinant Human Deoxycytidine Kinase (Dck)

Images

Western Blot analysis of immunized recombinant protein using DCK antibody (10R-1380)

Specifications

Host Mouse
Clone 2243C2
Isotype IgG1
Method of Purification DCK antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer DCK antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

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Images

  • Western Blot analysis of immunized recombinant protein using DCK antibody (10R-1380)

Availability: In stock

Price: $190.00
Size: 50 ug
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