DCX antibody (70R-5900)

Rabbit polyclonal DCX antibody

Synonyms Polyclonal DCX antibody, Anti-DCX antibody, XLIS antibody, Doublecortex; Lissencephaly X-Linked antibody, LISX antibody, DC antibody, DBCN antibody, SCLH antibody, Doublecortin antibody
Cross Reactivity Human,Mouse
Applications WB
Immunogen DCX antibody was raised using a synthetic peptide corresponding to a region with amino acids TAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPIS
Assay Information DCX Blocking Peptide, catalog no. 33R-8973, is also available for use as a blocking control in assays to test for specificity of this DCX antibody

Images

Western Blot analysis using DCX antibody (70R-5900)

DCX antibody (70R-5900) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 49 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of DCX antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The protein contains two doublecortin domains, which bind microtubules. In addition, DCX interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.

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Images

  • Western Blot analysis using DCX antibody (70R-5900) | DCX antibody (70R-5900) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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