DDR1 antibody (10R-1994)

Mouse monoclonal DDR1 antibody

Synonyms Monoclonal DDR1 antibody, Anti-DDR1 antibody, mammarian carcinoma kinase 10 antibody, epithelial discoidin domain receptor 1 antibody, neuroepithelium antibody, discoidin domain receptor 1 antibody, nep antibody, CAK antibody, DDR1, EDDR1 antibody, MCK10 antibody, cell adhesion kinase antibody, DDR 1, DDR-1, Drd1 antibody, DDR-1 antibody, DDR 1 antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen DDR1 antibody was raised in Mouse using a purified recombinant fragment of DDR1(aa602-681) expressed in E. coli as the immunogen.

Images

Western Blot analysis using DDR1 antibody (10R-1994)

Western Blot showing DDR1 antibody used against truncated MBP-DDR1 recombinant protein (1).

Specifications

Host Mouse
Clone 2G4E12
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance DDR1 is a Receptor Tyrosine Kinase that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain.

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Images

  • Western Blot analysis using DDR1 antibody (10R-1994) | Western Blot showing DDR1 antibody used against truncated MBP-DDR1 recombinant protein (1).

Availability: In stock

Price: $295.00
Size: 100 ul
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