DDR2 antibody (10R-2113)

Mouse monoclonal DDR2 antibody

Synonyms Monoclonal DDR2 antibody, Anti-DDR2 antibody, Discoidin domain receptor tyrosine kinase 2 antibody, TKT antibody, NTRKR3 antibody, Discoidin domain receptor 2 antibody, DDR2, DDR 2, DDR-2, DDR 2 antibody, DDR-2 antibody
Cross Reactivity Human
Applications ELISA, IF, IHC, WB
Immunogen DDR2 antibody was raised in Mouse using a purified recombinant fragment of human DDR2 expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using DDR2 antibody (10R-2113) (DDR2 antibody)

Confocal immunofluorescence analysis of A549 cells using DDR2 antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 3B11E4
Isotype IgG2a
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance DDR2 is a receptor tyrosine kinase. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction.

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Images

  • Immunofluorescent staining using Western Blot analysis using DDR2 antibody (10R-2113) (DDR2 antibody) | Confocal immunofluorescence analysis of A549 cells using DDR2 antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
  • Western Blot analysis using DDR2 antibody (10R-2113) | Western Blot showing DDR2 antibody used against truncated DDR2 recombinant protein.
  • Immunohistochemical staining using DDR2 antibody (10R-2113) | Immunohistochemical analysis of paraffin-embedded human skeletal musle tissues using DDR2 antibody.

Availability: In stock

Price: $375.00
Size: 100 ul
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