Desmoplakin 1 + 2 antibody (10R-D108ax)

Mouse monoclonal Desmoplakin 1 + 2 antibody

Synonyms Monoclonal Desmoplakin 1 + 2 antibody, Anti-Desmoplakin 1 + 2 antibody, Desmoplakin 1/2 antibody
Specificity Bovine desmoglein 1/2
Cross Reactivity Bovine, chicken, human, mouse, rat
Applications IF, IHC-F, WB
Immunogen Desmoplakin 1/2 antibody was raised in mouse using bovine desmoplakin 1&2 as the immunogen.

Specifications

Host Mouse
Clone DP 1 + 2-2.15
Isotype IgG1
Method of Purification Protein A affinity chromatography
Form & Buffer Supplied as a lyophilized powder. Reconstitute in 1 ml dist. water (final solution contains 0.09 % NaN3, 0.5% BSA in PBS buffer, pH 7.4)

Usage & Assay Information

Usage Recommendations IHC-F: 1:10

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin.

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Availability: In stock

Price: $350.00
Size: 50 ug
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