DGKA antibody (10R-8135)

Mouse monoclonal DGKA antibody

Synonyms Monoclonal DGKA antibody, Anti-DGKA antibody, Diacylglycerol Kinase Alpha 80Kda antibody, DAGK antibody, DAGK1 antibody, DGK-alpha antibody, MGC12821 antibody, MGC42356 antibody, DGKA
Cross Reactivity Human
Applications IP, WB
Immunogen DGKA antibody was raised in Mouse using an Escherichia coli cell-expressed, affinity-purified glutathione S-transferase fusion protein of a C-terminal portion (part of the catalytic domain) of rat DGKu as the immunogen.


Host Mouse
Clone M5a
Isotype None
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations Optimal dilution should be determined by titration

General Information

Biological Significance Diacylglycerol kinase alpha is an enzyme that in humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Tissue specificity: lymphocytes and oligodendroglial cells. Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-generating enzymes.

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Availability: In stock

Price: $395.00
Size: 100 ug
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