Diazepam Binding Inhibitor protein (30R-3011)

Purified recombinant Diazepam Binding Inhibitor protein

Synonyms DBI protein, Diazepam Binding Inhibitor protein, ACBD 1 protein, ACBD1 protein, ACBP protein, Acyl CoA binding domain containing 1 protein, Acyl CoA binding protein protein, acyl coenzyme A binding protein protein, acyl-Coenzyme A binding domain containing 1 protein, CCK RP protein, CCKRP protein, Cholecystokinin releasing peptide trypsin sensitive protein, endozepine protein, EP protein, GABA receptor modulator acyl Coenzyme A binding protein protein, GABA receptor modulator protein, MGC70414 protein
Species Human
Protein Type Recombinant
Applications WB

Images

Western Blot analysis using Diazepam Binding Inhibitor protein (30R-3011)

Specifications

Expression System E.coli
Purity > 95% pure
Molecular Weight 38 kDa
Form & Buffer Supplied in lyophilized form from 20mM HEPES, pH 7.4

Storage & Safety

Storage Store at -20 deg C. After reconstitution store at -80 deg C. Avoid frequent freeze/thaw cycles

General Information

Biological Significance Diazepam Binding Inhibitor (DBI) is a highly conserved 10 kDa polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central and peripheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer’s disease.

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Images

  • Western Blot analysis using Diazepam Binding Inhibitor protein (30R-3011) |

Availability: In stock

Price: $175.00
Size: 500 ug
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