DIRAS1 protein (His tag) (80R-1486)

Purified recombinant Human DIRAS1 protein

Synonyms RIG protein, Di-Ras1 protein, DIRAS-1 protein, FLJ42681 protein, DIRAS 1 protein, DIRAS 1, GBTS1 protein, DIRAS1, DIRAS-1, GTP-binding protein Di-Ras1.
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of DIRAS1 protein (His tag) (80R-1486)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-195 amino acids: MGSSHHHHHH SSGLVPRGSH MPEQSNDYRV VVFGAGGVGK SSLVLRFVKG TFRDTYIPTI EDTYRQVISC DKSVCTLQIT DTTGSHQFPA MQRLSISKGH AFILVFSVTS KQSLEELGPI YKLIVQIKGS VEDIPVMLVG NKCDETQREV DTREAQAVAQ EWKCAFMETS AKMNYNVKEL FQELLTLETR RNMSLNIDGK RSGKQKRTDR VKGKC
Expression System E.coli
Purity > 95% pure
Molecular Weight 24.1 kDa (215aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 1mM DTT, 0.1M NaCl and 1mM EDTA.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases. Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. Recombinant human DIRAS1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of DIRAS1 protein (His tag) (80R-1486) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $255.00
Size: 50 ug
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