Dkk1 protein (His tag) (80R-1115)

Purified recombinant Human Dkk1 protein

Synonyms Dkk 1, Dickkopf-1 protein, DKK1, Dickkopf related protein 1 protein, Dickkopf 1 like protein, Dickkopf-related protein 1 Dickkopf 1 protein, DKK 1 protein, hDkk 1 protein, Dkk-1 protein, Dkk 1 protein, Dickkopf homolog 1 protein, SK protein, Dkk1, hDkk-1 protein, Dkk-1
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Dkk1 protein (His tag) (80R-1115)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 32-266 amino acids: ADPTLNSVLN SNAIKNLPPP LGGAAGHPGS AVSAAPGILY PGGNKYQTID NYQPYPCAED EECGTDEYCA SPTRGGDAGV QICLACRKRR KRCMRHAMCC PGNYCKNGIC VSSDQNHFRG EIEETITESF GNDHSTLDGY SRRTTLSSKM YHTKGQEGSV CLRSSDCASG LCCARHFWSK ICKPVLKEGQ VCTKHRRKGS HGLEIFQRCY CGEGLSCRIQ KDHHQASNSS RLHTCQRHSG RLVPRGSHHH HHH
Expression System Hi-5 cells
Purity > 85% pure
Molecular Weight 27.8 kDa (253 aa) (On SDS-PAGE under denatured condition, apparent molecular weight of glycosylated rhDkk-1 protein will be appeared at approximately 40 kDa)
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol.
Concentration 0.25 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance Dickkopf-related protein 1, also known as Dkk-1, is a member of the Dkk protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Recombinant human Dkk-1 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of Dkk1 protein (His tag) (80R-1115) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $310.00
Size: 10 ug
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