DNAL1 protein (His tag) (80R-2662)
Purified recombinant Human DNAL1 protein (His tag)
|Synonyms||axonemal protein, Dynein light chain 1 protein, DNAL1, DNAL 1 protein, CILD 16 protein, CILD16 protein, DNAL-1 protein, CILD-16 protein, DNAL-1, DNAL 1, C14orf168 protein|
SDS-PAGE analysis of DNAL1 protein (His tag) (80R-2662)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-190 aa: MGSSHHHHHH SSGLVPRGSH MGSMAKATTI KEALARWEEK TGQRPSEAKE IKLYAQIPPI EKMDASLSML ANCEKLSLST NCIEKIANLN GLKNLRILSL GRNNIKNLNG LEAVGDTLEE LWISYNFIEK LKGIHIMKKL KILYMSNNLV KDWAEFVKLA ELPCLEDLVF VGNPLEEKHS AENNWIEEAT KRVPKLKKLD GTPVIKGDEE EDN|
|Method of Purification||DNAL1 protein was purified using Protein G affinity chromatography|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||DNAL1 is an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. DNAL1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants. Recombinant human DNAL1 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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