DNM1 antibody (Ser774) (70R-14968)

Sheep polyclonal DNM1 antibody (Ser774)

Synonyms Polyclonal DNM1 antibody, Anti-DNM1 antibody, DNM 1 antibody, DNM-1 antibody, DNM1, Dynamin 1 antibody, DNM antibody, Dynamin antibody
Applications IF, IHC, WB

Images

Western Blot analysis using DNM1 antibody (Ser774) (70R-14968)

Western blot of rat hippocampal lysate stimulated with forskolin showing specific immunolabeling of ~95k dynamin phosphorylated at Ser774 (Control)

Specifications

Host Sheep
Method of Purification DNM1 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IF: 1:1000, IHC: 1:1000

General Information

Biological Significance This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15.

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Images

  • Western Blot analysis using DNM1 antibody (Ser774) (70R-14968) | Western blot of rat hippocampal lysate stimulated with forskolin showing specific immunolabeling of ~95k dynamin phosphorylated at Ser774 (Control)

Availability: In stock

Price: $335.00
Size: 100 ul
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