DOK1 antibody (70R-10511)

Affinity purified rabbit polyclonal DOK1 antibody

Synonyms Polyclonal DOK1 antibody, Anti-DOK1 antibody, MGC117395 antibody, P62DOK antibody, MGC138860 antibody, 62kDa, DOK 1 antibody, DOK 1, DOK-1, docking protein 1, DOK1, DOK-1 antibody, downstream of tyrosine kinase 1 antibody
Cross Reactivity Human
Applications WB
Immunogen DOK1 antibody was raised in rabbit using the C terminal of DOK1 as the immunogen

Images

Western Blot analysis using DOK1 antibody (70R-10511)

DOK1 antibody (70R-10511) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

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Images

  • Western Blot analysis using DOK1 antibody (70R-10511) | DOK1 antibody (70R-10511) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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