DOK2 antibody (70R-10517)

Affinity purified rabbit polyclonal DOK2 antibody

Synonyms Polyclonal DOK2 antibody, Anti-DOK2 antibody, DOK 2, DOK-2 antibody, 56kDa antibody, DOK-2, DOK2, docking protein 2, DOK 2 antibody
Cross Reactivity Human, Mouse, Rat, Bovine
Applications WB
Immunogen DOK2 antibody was raised in rabbit using the C terminal of DOK2 as the immunogen
Assay Information DOK2 Blocking Peptide, catalog no. 33R-7536, is also available for use as a blocking control in assays to test for specificity of this DOK2 antibody

Images

Western Blot analysis using DOK2 antibody (70R-10517)

Western Blot showing DOK2 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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Images

  • Western Blot analysis using DOK2 antibody (70R-10517) | Western Blot showing DOK2 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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