DSTN protein (His tag) (80R-2336)

Purified recombinant Human DSTN Protein (His tag)

Synonyms Destrin (actin depolymerizing factor) protein, ACTDP protein, bA462D18.2 protein, ADF protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of DSTN protein (His tag) (80R-2336)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues MASGVQVADE VCRIFYDMKV RKCSTPEEIK KRKKAVIFCL SADKKCIIVE EGKEILVGDV GVTITDPFKH FVGMLPEKDC RYALYDASFE TKESRKEELM FFLWAPELAP LKSKMIYASS KDAIKKKFQG IKHECQANGP EDLNRACIAE KLGGSLIVAF EGCPVLEHHH HHH
Expression System E.coli
Purity > 95% pure
Molecular Weight 19.5 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Concentration 500 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1-2 weeks). Aliquot and store at -20 deg C to -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance DSTN is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. DSTN is a small phosphoinositide-sensitive actin-binding protein capable of depolymerizing actin-filaments in vitro. It is found in various epithelial and endothelial cells but is practically absent from adult mouse heart and skeletal muscle cells. DSTN shares 71% sequence homology with Cofilin, however the two proteins differ in their interaction with Actin. Recombinant human DSTN protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of DSTN protein (His tag) (80R-2336) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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