DUSP12 antibody (10R-8614)

Mouse monoclonal DUSP12 antibody

Synonyms Monoclonal DUSP12 antibody, Anti-DUSP12 antibody, DUSP12 antibody, dual specificity phosphatase 12 antibody, BOS_2683 antibody, dual specificity phosphatase T-DSP4 antibody, dual specificity phosphatase VH1 antibody, dual specificity protein phosphatase 12 antibody, dual specificity tyrosine phosphatase YVH1 antibody, DUSP1 antibody, ESTM36 antibody, GKAP antibody, glucokinase-associated dual specificity phosphatase antibody, LMW-DSP4 antibody, mVH1 antibody, serine/threonine specific protein phosphatase antibody, T-DSP4 antibody, VH1 antibody, YVH1 antibody, YVH1 protein-tyrosine phosphatase ortholog antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen DUSP12 antibody was raised in Mouse using a recombinant human protein purified from E.coli as the immunogen

Images

Western Blot analysis using DUSP12 antibody (10R-8614)

Specifications

Host Mouse
Clone AF28B2
Isotype IgG1 kappa
Method of Purification DUSP12 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB(1:5000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Dual specificity phosphatase (DUSP) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSPs can be divided into six subgroups on the basis of sequence similarity (PRLs, Cdc14 phosphatases, PTENs, myotubularins, MKPs, atypical DUSPs). DUSP inhibitors might be used to manipulate MAPK and cellular responses in both positive and negative ways. The regulated expression and activity of DUSP family members in different cells and tissues controls MAPK intensity and duration to determine the type of physiological response. DUSP12 (YVH1, GKAP) contains the consensus DUSP catalytic domain as well as an extended C-terminal domain of unknown function, thought to be related to its potential role in glucokinase regulation. It is localized in the cytoplasm and nucleus.

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Images

  • Western Blot analysis using DUSP12 antibody (10R-8614) |

Availability: In stock

Price: $295.00
Size: 100 ul
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