DUSP23 protein (His tag) (80R-2039)
Recombinant human DUSP23 protein (His tag)
|Synonyms||LDP-3 protein, DUSP-23 protein, DUSP-23, Dual specificity protein phosphatase 23 protein, VHZ protein, DUSP 23 protein, MOSP protein, DUSP23, DUSP25 protein, DUSP 23|
SDS-PAGE analysis of DUSP23 protein (His tag) (80R-2039)
SDS-PAGE gel analysis of DUSP23 protein (His tag) where the figure is annotated with amount of protein run on the gel.
|Residues||1-150 amino acids: MGSSHHHHHH SSGLVPRGSH MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK|
|Purity||> 90% pure|
|Molecular Weight||18.8 kDa (170aa), confirmed by MALDI-TOF|
|Form & Buffer||Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 100mM NaCl|
Usage & Assay Information
|Usage Recommendations||DUSP23 protein (His tag) has been used in SDS-PAGE, and may be suitable for use in other applications, to be determined by the end user.|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||DUSP23, also known as low molecular mass dual specificity phosphatase 3(LDP-3), belongs to the protein-tyrosine phosphatase family. This protein is a protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. This protein able to enhance activation of JNK and p38(MAPK14). Recombinant human DUSP23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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