DUSP3 antibody (70R-14299)

Affinity purified Rabbit polyclonal DUSP3 antibody

Synonyms Polyclonal DUSP3 antibody, Anti-DUSP3 antibody, DUSP 3, DUSP3 antibody, serine/threonine specific protein phosphatase antibody, dual specificity protein phosphatase 3 antibody, dual specificity protein phosphatase VHR antibody, DUSP3, vaccinia H1-related phosphatase antibody, VHR antibody, vaccinia virus phosphatase VH1-related antibody, DUSP 3 antibody, DUSP-3 antibody, DUSP-3
Applications WB
Immunogen DUSP3 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human DUSP3, identical to the related rat and Rabbit sequences, as the immunogen

Images

Western blot analysis using DUSP3 antibody (70R-14299)

Lane 1: Rat Testis Tissue Lysate, Lane 2: SKOV Cell Lysate, Lane 3: M453 Cell Lysate

Specifications

Host Rabbit
Isotype IgG
Method of Purification DUSP3 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western blot analysis using DUSP3 antibody (70R-14299) | Lane 1: Rat Testis Tissue Lysate, Lane 2: SKOV Cell Lysate, Lane 3: M453 Cell Lysate

Availability: In stock

Price: $270.00
Size: 100 ug
OR
Shipping
View Our Distributors