DUSP4 antibody (10R-1447)

Mouse monoclonal DUSP4 antibody

Synonyms Monoclonal DUSP4 antibody, Anti-DUSP4 antibody, DUSP 4 antibody, MKP2 antibody, Dual specificity phosphatase 4 antibody, DUSP-4 antibody, TYP antibody, DUSP4, HVH2 antibody, MKP-2 antibody, DUSP-4, DUSP 4
Specificity Human DUSP4
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen DUSP4 antibody was raised in mouse using recombinant Human Dual Specificity Phosphatase 4 (Dusp4)

Images

Western Blot analysis of immunized recombinant protein using DUSP4 antibody (10R-1447)

Specifications

Host Mouse
Clone 2295E1a
Isotype IgG1
Method of Purification DUSP4 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer DUSP4 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.

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Images

  • Western Blot analysis of immunized recombinant protein using DUSP4 antibody (10R-1447)

Availability: In stock

Price: $190.00
Size: 50 ug
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