Dynamin 1 antibody (10R-2018)

Mouse monoclonal Dynamin 1 antibody

Synonyms Monoclonal Dynamin 1 antibody, Anti-Dynamin 1 antibody, DNM antibody, DNM1 antibody, Dynamin 1, Dynamin 1, Dynamin -1, Dynamin 1 antibody, Dynamin -1 antibody
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen Dynamin 1 antibody was raised in Mouse using a purified recombinant fragment of human Dynamin-1 expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using Dynamin 1 antibody (10R-2018)

Immunohistochemical analysis of paraffin-embedded human lymph tissue (A), glioma tissue (B) and cerebellum tissue (C), showing membrane localization using Dynamin1 antibody with DAB staining

Specifications

Host Mouse
Clone 3G4B6
Isotype IgG2a
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Dynamin 1 is a member of the dynamin subfamily of GTP-binding proteins. The protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

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Images

  • Immunohistochemical staining using Dynamin 1 antibody (10R-2018) | Immunohistochemical analysis of paraffin-embedded human lymph tissue (A), glioma tissue (B) and cerebellum tissue (C), showing membrane localization using Dynamin1 antibody with DAB staining
  • Western Blot analysis using Dynamin 1 antibody (10R-2018) | Western Blot showing Dynamin1 antibody used against C6 (1), NIH/3T3 (2), SKN-SH (3), LN18 (4), SHSY5Y (5) cell lysate and rat brain tiisues lysate (6).

Availability: In stock

Price: $425.00
Size: 100 ul
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