E Cadherin antibody (10R-7947)

Mouse monoclonal E Cadherin antibody

Synonyms Monoclonal E Cadherin antibody, Anti-E Cadherin antibody, Cadherin 1 antibody, Type 1 E-Cadherin antibody, Arc-1 antibody, CD324 antibody, CDHE antibody, ECAD antibody, LCAM antibody, UVO antibody, E Cadherin
Specificity Recognizes both the 120 kD E-cadherin and its 80 kD trypsin-resistant extracellular part
Cross Reactivity Human, Zebrafish
Applications FC, IHC, IHC-F, WB
Immunogen E Cadherin antibody was raised in Mouse using MCF-7/AZ cells expressing E-cadherin at their cell surface as the immunogen.

Specifications

Host Mouse
Clone MB2
Isotype IgG2b
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations FC: 1:100-1:200, IHC: 1:100-1:200, WB: 1:100-1:1000

General Information

Biological Significance Cadherins are a class of type-1 transmembrane proteins. They play important roles in cell adhesion, ensuring that cells within tissues are bound together. They are dependent on calcium (Ca2+) ions to function, hence their name. The cadherin superfamily includes cadherins, protocadherins, desmogleins, and desmocollins, and more. In structure, they share cadherin repeats, which are the extracellular Ca2+-binding domains. There are multiple classes of cadherin molecule, each designated with a prefix (in general, noting the type of tissue with which it is associated).

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Availability: In stock

Price: $410.00
Size: 100 ug
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