E Cadherin antibody (10R-7949)

Mouse monoclonal E Cadherin antibody

Synonyms Monoclonal E Cadherin antibody, Anti-E Cadherin antibody, Cadherin 1 antibody, Type 1 E-Cadherin antibody, Arc-1 antibody, CD324 antibody, CDHE antibody, ECAD antibody, LCAM antibody, UVO antibody, E Cadherin
Specificity Recognizes both the 120 kD E-cadherin and its 80 kD trypsin-resistant extracellular part
Cross Reactivity Human
Applications IHC, IHC-F, WB
Immunogen E Cadherin antibody was raised in Mouse using affinity purified 80 kD extracellular fragments of E-cadherin derived from tryptic digestion of A-431 human vulva carcinoma cells as the immunogen.

Specifications

Host Mouse
Clone 6F9
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:25-1:100, WB: 1:50-1:500

General Information

Biological Significance Cadherins are a superfamily of transmembrane glycoproteins that contain cadherin repeats of approximately 100 residues in their extracellular domain. Cadherins mediate calcium-dependent cell-cell adhesion and play critical roles in normal tissue development. The classic cadherin subfamily includes N-, P-, R-, B-, and E-cadherins, as well as about ten other members that are found in adherens junctions, a cellular structure near the apical surface of polarized epithelial cells.

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Availability: In stock

Price: $410.00
Size: 100 ug
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