E Cadherin antibody (10R-7951)

Mouse monoclonal E Cadherin antibody

Synonyms Monoclonal E Cadherin antibody, Anti-E Cadherin antibody, Cadherin 1 antibody, Type 1 E-Cadherin antibody, Arc-1 antibody, CD324 antibody, CDHE antibody, ECAD antibody, LCAM antibody, UVO antibody, E Cadherin
Specificity Recognizes both the 120 kD E-cadherin and its 80 kD trypsin-resistant extracellular part.. The epitope is present within amino acid residues 9-21 of mature human E-cadherin
Cross Reactivity Human
Applications WB
Immunogen E Cadherin antibody was raised in Mouse using the synthetic peptide corresponding to amino acids 30-43 of mature human E-cadherin coupled to keyhole limpet hemocyanin as the immunogen.

Specifications

Host Mouse
Clone SEC21
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations WB: 1:100-1:1000

General Information

Biological Significance The cadherin superfamily comprises a large number of cell surface glycoproteins with one or more cadherin repeats, which are involved in Ca2+-dependent cell-cell adhesion. Classical cadherins contain five extracellular cadherin repeats and a conserved cytoplasmic region that interacts with the actin cytoskeleton via catenins. In addition to cell adhesion, cadherins also mediate morphogenesis, cytoskeletal organization, and cell migration. In addition to the classical cadherins, the cadherin superfamily also includes desmosomal cadherins, protocadherins, 7TM cadherins, FAT family cadherins, and T-cadherin.

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Availability: In stock

Price: $410.00
Size: 100 ug
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