EGF protein (30R-AE025)

Purified recombinant Human EGF protein

Synonyms URG protein, Urogastrone protein, Epidermal Growth Factor protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of EGF protein corresponding to amino acids MNSNTGCPPS YDGYCLNGGV CMYVESVDRY VCNCVIGYIG ERCQHRDLRW WKLR.
Expression System E.coli
Purity > 98% pure
Molecular Weight 6.2 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is 1 x 10^7 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF alpha and VGF (vaccinia virus growth factor).

References
Add a Paper

Li H, Dusseault J, Larose L

Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression

Cell Communication and Signaling

Volume: 12 Issue: 1 Page: 71 PMID: 25398386 DOI: 10.1186/s12964-014-0071-9

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: $225.00
Size: 100 ug
OR
Shipping
View Our Distributors