EGFR protein (30R-3147)

Purified recombinant EGFR protein

Synonyms Proto oncogene c ErbB 1 protein, Receptor tyrosine protein kinase erbB 1 protein, Epidermal growth factor receptor protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Images

Western blot analysis using EGFR protein (30R-3147)

Specifications

Expression System E.coli
Purity > 90% pure
Molecular Weight 75 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 6M guanidine hydrochloride and 20mM Tris buffer

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance EGFR is the cell surface receptor for EGF, but also for other members of the EGF family, such as TGF-alpha, BTC/betacellulin, AREGAREGB/amphiregulin, HBEGF, GP30 and vaccinia virus growth factor. Ligand binding triggers a conformation change, leading to activation of the kinase and subsequent phosphorylation of down-stream protein kinases. Is involved in the control of cell growth, proliferation and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western blot analysis using EGFR protein (30R-3147)
  • Western blot analysis using COX5B protein (GST tag) (30R-3147) |

Availability: In stock

Price: $210.00
Size: 50 ug
OR
Shipping
View Our Distributors