EIF2AK3 antibody (10R-2262)

Mouse monoclonal EIF2AK3 antibody

Synonyms Monoclonal EIF2AK3 antibody, Anti-EIF2AK3 antibody, Eukaryotic translation initiation factor 2-alpha kinase 3 antibody, EIFAK3-2, WRS antibody, EIFAK3 2 antibody, EIFAK3-2 antibody, Pancreatic eIF2-alpha kinase antibody, PERK antibody, EIF2AK3, EIFAK3 2
Cross Reactivity Human
Applications ELISA, WB
Immunogen EIF2AK3 antibody was raised in Mouse using a purified recombinant fragment of human EIF2AK3 expressed in E. coli as the immunogen.

Images

Western Blot analysis using EIF2AK3 antibody (10R-2262)

Western Blot showing EIF2AK3 antibody used against HEK293 (1) and EIF2AK3 (AA: 929-1116)-hIgGFc transfected HEK293 (2) cell lysate.

Specifications

Host Mouse
Clone 5G5
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

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Images

  • Western Blot analysis using EIF2AK3 antibody (10R-2262) | Western Blot showing EIF2AK3 antibody used against HEK293 (1) and EIF2AK3 (AA: 929-1116)-hIgGFc transfected HEK293 (2) cell lysate.

Availability: In stock

Price: $345.00
Size: 100 ul
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