Elastase antibody (10R-E102a)

Mouse monoclonal Elastase antibody

Synonyms Monoclonal Elastase antibody, Anti-Elastase antibody
Specificity Human elastase
Cross Reactivity To be determined by end-user
Applications ELISA
Immunogen Elastase antibody was raised in mouse using purified human neutrophil elastase as the immunogen.

Specifications

Host Mouse
Clone 203
Isotype IgG1
Form & Buffer Purified by column chromatography and supplied as a liquid in PBS.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations ELISA: 1:6,400

Storage & Safety

Storage Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Elastase breaks down elastin, an elastic fiber that, together with collagen, determines the mechanical properties of connective tissue. The neutrophil form breaks down the Outer membrane protein A (OmpA) of E. coli and other Gram-negative bacteria. Elastase also has the important immunological role of breaking down Shigella virulence factors.

References
Add a Paper

Philip L. Davies, Nicola C. Maxwell, Sailesh Kotecha, O. Brad Spiller

Monoclonal anti-neutrophil elastase antibody characterisation: Ability to block function, detect free versus serpin-complexed enzyme and stain intracellular granule

Journal of Immunological Methods

Volume: 336 Issue: 2 Page: 175-182 DOI: 10.1016/j.jim.2008.04.010

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Availability: In stock

Price: $425.00
Size: 500 ug
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