Elastase protein (30-AE35)

Purified native Human Elastase protein

Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human neutrophils
Purity > 95% pure
Molecular Weight 29.5 kDa
Form & Buffer Supplied as a lyophilised powder.

Usage & Assay Information

Bioactivity 20-22 units/mg - One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Meo-suc-ala-pro-val-pNA per minute at 25o C in 100 mM Tris-HCl, pH 7.5, with 500 mM NaCl.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance Elastase degrades elastin, collagen, and proteoglycan and has been implicated in the development of pulmonary emphesema and rheumatoid arthritis.

References
Add a Paper

Birgit Riepl, Susanne Grässel, Reiner Wiest, Martin Fleck, Rainer H Straub

Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

Arthritis Research and Therapy

Issue: 12:R110 DOI: 10.1186/ar3044

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Availability: In stock

Price: $297.00
Size: 100 ug
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