ELK1 antibody (10R-1943)
Mouse monoclonal ELK1 antibody
|Synonyms||Monoclonal ELK1 antibody, Anti-ELK1 antibody, ELK 1 antibody, ELK-1 antibody, ELK1, ELK 1, ELK-1 antibody, ELK 1 antibody, ELK-1|
|Immunogen||ELK1 antibody was raised in Mouse using a purified recombinant fragment of ELK1 expressed in E. coli as the immunogen.|
Western Blot analysis using ELK1 antibody (10R-1943)
Western Blot showing ELK1 antibody used against truncated ELK1 recombinant protein (1) and K562 cell lysate (2).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000,|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||The transcription factor ELK1 is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11. 2 and stimulates transcription. binds to purine-rich DNA sequences. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus, It appears to be a direct target of activated MAP kinase.|
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