ENA78 protein (30R-AE023)

Purified recombinant Human ENA78 protein

Synonyms ENA-78, ENA-78 protein, ENA78, ENA-78 protein, ENA 78, ENA 78 protein, CXCL5 protein, Epithelial Neutrophil Activating Peptide-78 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of ENA78 protein corresponding to amino acids LRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QCSKVEVVAS LKNGKEICLD PEAPFLKKVI QKILDGGNKE N.
Expression System E.coli
Purity > 98% pure
Molecular Weight 8 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The Mouse homolog of ENA-78 is called LIX. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.

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Availability: In stock

Price: $225.00
Size: 20 ug
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