EPHA2 antibody (10R-2017)

Mouse monoclonal EPHA2 antibody

Synonyms Monoclonal EPHA2 antibody, Anti-EPHA2 antibody, EPHA2, EPHA 2, EPHA-2 antibody, Ephrin receptor EPHA2 antibody, epoxide hydrolase 1 microsomal (xenobiotic) antibody, EPHA 2 antibody, EPHA-2
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen EPHA2 antibody was raised in Mouse using a purified recombinant fragment of EPHA2 expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using EPHA2 antibody (10R-2017)

Immunohistochemical analysis of paraffin-embedded human skin carcinoma (left) and pancreas carcinoma (right) tissue, showing cytoplasmic localization using EphA2 antibody with DAB staining.

Specifications

Host Mouse
Clone 1B3C7
Isotype IgM
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTk). Eph RTks and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EPHA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer.

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Images

  • Immunohistochemical staining using EPHA2 antibody (10R-2017) | Immunohistochemical analysis of paraffin-embedded human skin carcinoma (left) and pancreas carcinoma (right) tissue, showing cytoplasmic localization using EphA2 antibody with DAB staining.
  • Western Blot analysis using EPHA2 antibody (10R-2017) | Western Blot showing EphA2 antibody used against NIH/3T3 cell lysate.

Availability: In stock

Price: $345.00
Size: 100 ul
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