EphA3 antibody (10R-1996)
Mouse monoclonal EphA3 antibody
|Synonyms||Monoclonal EphA3 antibody, Anti-EphA3 antibody, EphA-3, EPH receptor A3 antibody, EphA 3 antibody, EphA3, EphA 3, EphA-3 antibody|
|Immunogen||EphA3 antibody was raised in Mouse using a purified recombinant fragment of EphA3(aa751-983) expressed in E. coli as the immunogen.|
Western Blot analysis using EphA3 antibody (10R-1996)
Western Blot showing EphA3 antibody used against truncated Trx-EphA3 recombinant protein (1) and truncated EphA3 (aa566-983)-hIgGFc transfected CHO-K1 cell lysate (2).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||EphA3 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.|
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