EPM2A antibody (10R-1110)

Mouse monoclonal EPM2A antibody

Synonyms Monoclonal EPM2A antibody, Anti-EPM2A antibody, EPMA -2, LD antibody, epilepsy antibody, EPMA -2 antibody, EPMA 2 antibody, EPMA 2, EPM2A, progressive myoclonus type 2A Lafora disease (laforin) antibody, LDE antibody, Laforin isoform a antibody, epilepsy progressive myoclonus type 2 Lafora disease (laforin) antibody
Specificity Human
Cross Reactivity Human
Applications ELISA, WB
Immunogen EPM2A antibody was raised in mouse using recombinant human EPM2A (243-331aa) purified from E. coli as the immunogen.

Images

Western blot analysis using EPM2A antibody (10R-1110)

Figure is annotated with cell line lysates which were probed by the antibody

Specifications

Host Mouse
Clone k2A3
Isotype IgG1 kappa
Source Anti-human EPM2A antibody, clone k2A3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human EPM2A protein.
Method of Purification EPM2A antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules. Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2(EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy.

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Images

  • Western blot analysis using EPM2A antibody (10R-1110) | Figure is annotated with cell line lysates which were probed by the antibody

Availability: In stock

Price: $265.00
Size: 100 ul
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