ESAT6 protein (His tag) (80R-2222)
Purified recombinant Mycobacterium tuberculosis ESAT6 Protein (His tag)
|Synonyms||protein, ESAT 6, ESAT-6, Early secretory antigenic target protein, ESAT-6 protein, ESAT6, ESAT 6 protein, 6 kDa protein|
Coomassie Blue stained SDS-PAGE of ESAT6 protein (His tag) (80R-2222)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||ADPMTEQQWN FAGIEAAASA IQGNVTSIHS LLDEGKQSLT KLAAAWGGSG SEAYQGVQQK WDATATELNN ALQNLARTIS EAGQAMASTE GNVTGMFAHH HHHH|
|Expression System||Hi-5 cells|
|Purity||> 90% pure|
|Molecular Weight||11 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer, pH 8.0, containing, 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||ESAT-6, the 6 kDa early secretory antigenic target of Mycobacterium tuberculosis, is a secretory protein and potent T cell antigen. It is used in tuberculosis diagnosis by the whole blood interferon ? test QuantiFERON-TB Gold, in conjunction with CFP-10 and TB7.7. ESAT-6 has been shown to directly bind to the TLR2 receptor, inhibiting downstream signal transduction.|
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