ESR1 antibody (10R-2243)

Mouse monoclonal ESR1 antibody

Synonyms Monoclonal ESR1 antibody, Anti-ESR1 antibody, ESR1, ESR 1, ESR-1, ESR 1 antibody, ESR-1 antibody
Cross Reactivity Human
Applications ELISA, IF, IHC, WB
Immunogen ESR1 antibody was raised in Mouse using a purified recombinant fragment of human ESR1 expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using ESR1 antibody (10R-2243) (ESR1 antibody)

Immunofluorescence analysis of Hela cells using ESR1 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Specifications

Host Mouse
Clone 6B6
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

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Images

  • Immunofluorescent staining using Western Blot analysis using ESR1 antibody (10R-2243) (ESR1 antibody) | Immunofluorescence analysis of Hela cells using ESR1 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Western Blot analysis using ESR1 antibody (10R-2243) | Western Blot showing ESR1 antibody used against MCF-7 (1), T47D (2) and SKBR3 (3) cell lysate.
  • Immunohistochemical staining using ESR1 antibody (10R-2243) | Immunohistochemical analysis of paraffin-embedded mammary cancer tissues using ESR1 antibody with DAB staining.

Availability: In stock

Price: $345.00
Size: 100 ul
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