Factor VIII antibody (10R-2035)
Mouse monoclonal Factor VIII antibody
|Synonyms||Monoclonal Factor VIII antibody, Anti-Factor VIII antibody, F8 antibody, FVIII antibody, AHF antibody, Factor 8 antibody, Anti hemophilic factor antibody|
|Immunogen||Factor VIII antibody was raised in Mouse using a purified recombinant fragment of Factor VIII expressed in E. coli as the immunogen.|
Western Blot analysis using Factor VIII antibody (10R-2035)
Western Blot showing F8 antibody used against truncated Trx-F8 recombinant protein (1).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Factor VIII is an essential blood clotting factor also known as anti-hemophilic factor (AHF). In humans, Factor VIII is encoded by the F8 gene. Defects in this gene results in hemophilia A, a well known recessive X-linked coagulation disorder. Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids forms a complex that converts factor X to the activated form Xa.|
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