FAK1 antibody (10R-8522)

Mouse monoclonal FAK1 antibody

Synonyms Monoclonal FAK1 antibody, Anti-FAK1 antibody, PTK2 antibody, PTK2 protein tyrosine kinase 2 antibody, BOS_13717 antibody, Fadk antibody, FADK 1 antibody, fak antibody, FAK1 antibody, FAK-related non-kinase polypeptide antibody, focal adhesion kinase antibody, focal adhesion kinase 1 antibody, focal adhesion kinase 56D ortholog antibody, focal adhesion kinase pp125FAK antibody, focal adhesion kinase-related nonkinase antibody, FRNK antibody, p125FAK antibody, p41/p43FRNK antibody, pp125FAK antibody, PPP1R71 antibody, protein phosphatase 1 regulatory subunit 71 antibody, protein phosphatase 1 antibody, regulatory subunit 71 antibody, protein tyrosine kinase 2 antibody, protein-tyrosine kinase 2 antibody
Cross Reactivity Human, Mouse, Rat
Applications ELISA, IP, WB
Immunogen FAK1 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-Fak1. a.a.706-1052) as the immunogen

Images

Western Blot analysis using FAK1 antibody (10R-8522)

Specifications

Host Mouse
Clone 63D5
Isotype IgG1 kappa
Method of Purification FAK1 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:5000, IP: 2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance AK is a nonreceptor and nonmembrane associated PTK which does not contain Src homology 2 (SH2) or SH3 protein interaction domains. The centrally located kinase domain of FAK is flanked by large N- and C-terminal noncatalytic domains. FAK links integrin receptors to intracellular signaling pathways that are important for cell growth, survival, and migration. Integrin receptor engagement with ligands such as fibronectin can stimulate FAK autophosphorylation which enables FAK to function within a network of integrin-stimulated signaling pathways leading to the activation of targets such as the ERK and JNK/mitogen-activated protein kinase pathways.

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Images

  • Western Blot analysis using FAK1 antibody (10R-8522) |

Availability: In stock

Price: $295.00
Size: 100 ul
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