FAK1 antibody (10R-8552)

Mouse monoclonal FAK1 antibody

Synonyms Monoclonal FAK1 antibody, Anti-FAK1 antibody, PTK2 antibody, PTK2 protein tyrosine kinase 2 antibody, BOS_13717 antibody, Fadk antibody, FADK 1 antibody, fak antibody, FAK1 antibody, FAK-related non-kinase polypeptide antibody, focal adhesion kinase antibody, focal adhesion kinase 1 antibody, focal adhesion kinase 56D ortholog antibody, focal adhesion kinase pp125FAK antibody, focal adhesion kinase-related nonkinase antibody, FRNK antibody, p125FAK antibody, p41/p43FRNK antibody, pp125FAK antibody, PPP1R71 antibody, protein phosphatase 1 regulatory subunit 71 antibody, protein phosphatase 1 antibody, regulatory subunit 71 antibody, protein tyrosine kinase 2 antibody, protein-tyrosine kinase 2 antibody
Cross Reactivity Human, Mouse
Applications WB
Immunogen FAK1 antibody was raised in Mouse using a recombinant human protein purified from E.coli(His-FAK1, 1-421 a.a.) as the immunogen

Images

Western Blot analysis using FAK1 antibody (10R-8552)

Specifications

Host Mouse
Clone 1D10
Isotype IgG2a kappa
Method of Purification FAK1 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance FAK links integrin receptors to intracellular signaling pathways that are important for cell growth, survival, and migration. Integrin receptor engagement with ligands such as fibronectin can stimulate FAK autophosphorylation which enables FAK to function within a network of integrin-stimulated signaling pathways leading to the activation of targets such as the ERK and JNK/mitogen-activated protein kinase pathways. Recent study reveals that FAK is essential for angiogenesis in the embryo, functions in heart development and modulates the response of cardiomyocytes to pressure overload in adult mice.

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Images

  • Western Blot analysis using FAK1 antibody (10R-8552) |

Availability: In stock

Price: $295.00
Size: 100 ul
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