FALZ antibody (10R-1453)

Mouse monoclonal FALZ antibody

Synonyms Monoclonal FALZ antibody, Anti-FALZ antibody, NURF301 antibody, BPTF antibody, FAC1 antibody, Bromodomain PHD finger transcription factor antibody
Specificity Human FALZ
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen FALZ antibody was raised in mouse using recombinant Human Bromodomain Phd Finger Transcription Factor (Bptf)

Images

Western Blot analysis of immunized recombinant protein using FALZ antibody (10R-1453)

Specifications

Host Mouse
Clone 2343C3a
Isotype IgG1
Method of Purification FALZ antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer FALZ antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation.

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Images

  • Western Blot analysis of immunized recombinant protein using FALZ antibody (10R-1453)

Availability: In stock

Price: $190.00
Size: 50 ug
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