FBLN5 antibody (10R-2135)

Mouse monoclonal FBLN5 antibody

Synonyms Monoclonal FBLN5 antibody, Anti-FBLN5 antibody, FIBL-5 antibody, Fibulin 5 antibody, FBLN 5, FBLN-5, FBLN 5 antibody, FBLN5, FIBL 5 antibody, FBLN-5 antibody, FBLN 5 antibody, FBLN-5 antibody
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen FBLN5 antibody was raised in Mouse using a purified recombinant fragment of FBLN5(aa242-448) expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using FBLN5 antibody (10R-2135)

Immunohistochemical analysis of paraffin-embedded human colon cancer (left) and breast cancer (right) showing cytoplasmic localization with DAB staining using FBLN5 antibody.

Specifications

Host Mouse
Clone 1G6A4
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance FBLN5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

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Images

  • Immunohistochemical staining using FBLN5 antibody (10R-2135) | Immunohistochemical analysis of paraffin-embedded human colon cancer (left) and breast cancer (right) showing cytoplasmic localization with DAB staining using FBLN5 antibody.
  • Western Blot analysis using FBLN5 antibody (10R-2135) | Western Blot showing FBLN5 antibody used against truncated FBLN5-His recombinant protein.

Availability: In stock

Price: $375.00
Size: 100 ul
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