FBXW7 antibody (70R-6541)

Rabbit polyclonal FBXW7 antibody raised against the C terminal of FBXW7

Synonyms Polyclonal FBXW7 antibody, Anti-FBXW7 antibody, FBXW-7, FBW7 antibody, DKFZp686F23254 antibody, AGO antibody, FBXW-7 antibody, FBX30 antibody, F-Box And Wd Repeat Domain Containing 7 antibody, SEL10 antibody, SEL-10 antibody, FBXW7, FBXW 7, FBXW 7 antibody, CDC4 antibody, FBXW6 antibody
Specificity FBXW7 antibody was raised against the C terminal of FBXW7
Cross Reactivity Human,Mouse,Drosophila
Applications WB
Immunogen FBXW7 antibody was raised using the C terminal of FBXW7 corresponding to a region with amino acids LKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVL
Assay Information FBXW7 Blocking Peptide, catalog no. 33R-5108, is also available for use as a blocking control in assays to test for specificity of this FBXW7 antibody

Images

Western blot analysis using FBXW7 antibody (70R-6541)

Tissue analyzed: Human Fetal Heart; Antibody Dilution: 1.0ug/ml

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 66 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of FBXW7 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.25 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance FBXW7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.

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Images

  • Western blot analysis using FBXW7 antibody (70R-6541) | Tissue analyzed: Human Fetal Heart; Antibody Dilution: 1.0ug/ml
  • Immunohistochemical staining using FBXW7 antibody (70R-6541) | Kidney
  • Western blot analysis using FBXW7 antibody (70R-6541) | Recommended FBXW7 Antibody Titration: 0.2-1 ug/ml
  • Western blot analysis using FBXW7 antibody (70R-6541) | Recommended FBXW7 Antibody Titration: 0.2-1 ug/ml
  • Immunofluorescent staining using FBXW7 antibody (70R-6541) | Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue.; Observed Staining: Cytoplasmic in cell bodies and processes of pinealocytesstained with FBXW7 antibody at 1:100

Availability: In stock

Price: $345.00
Size: 50 ug
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