FGF acidic protein (30R-AF043)

Purified recombinant Human FGF acidic protein

Synonyms FGF-1 protein, ECGF-beta protein, HBGF-1 protein, Fibroblast Growth Factor-acidic protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of FGF acidic protein corresponding to amino acids MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D.
Expression System E.coli
Purity > 95% pure
Molecular Weight 15.9 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is approximately 0.5 ng/ml corresponding to a specific activity of approximately 2 x 10^6 units/mg. Assay #2: The ED50 was det

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance FGF acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF acidic has the ability to signal through all the FGF receptors.

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Availability: In stock

Price: $225.00
Size: 50 ug
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